THE BEST SIDE OF PKRRATING

The activated enzyme then phosphorylates its key substrate, the translational initiation factor eIF2α. The ensuing translational arrest blocks viral replication. PKR belongs into a conserved relatives of four protein kinases (PKR, PERK, GCN2, HRI) that each one phosphorylate eIF2α in response to various stimuli12, click here triggering the integr